Deferoxamine is an novel iron chelator that is able to bind to free iron in a stable complex, it is also a bacterial siderophore produced by the Actinobacteria Streptomyces pilosus.
TRX-0237 mesylate (LMT-X; TRX0237; Leuco-MTx; LMTX; Hydromethylthionine mesylate), the mesylate salt of TRX 0237 which is currently in phase III clinical trials by TauRx, is a 2nd-generation tau protein aggregation and TDP-43 aggregation inhibitor with the potential for the treatment of Alzheimer’s disease (AD) and frontotemporal dementia.
Edonerpic, formerly known as T-817, is a neuroprotectant.
Anle138b is a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease.
ALZ-801 (ALZ801; BLU-8499; NRM-8499) is an orally bioavailable, small-molecule inhibitor of beta amyloid (Aβ) oligomer formation with the potential for treating Alzheimer’s disease (AD).
(2-Hydroxypropyl)-β-cyclodextrin is a cyclodextrin oligosaccharide that has been widely used drug delivery vehicle to improve the aqueous solubility, stability and bioavailability of chemical compounds.
Hoechst 34580 is a cell-permeable fluorescent dye for staining DNA and nuclei.
Geniposide is a novel and potent natural product
SNU-0039 (DWK-133) is an orally bioavailable inhibitor of β-amyloid protein aggregation with the potential to be used as an anti-Alzheimer’s agent.
Bavachinin (BVC; 7-O-Methylbavachin; Bavachinin A) is a naturally occuring compound isolated from the fruit of the traditional Chinese herb Fructus Psoraleae (FP).