Aripiprazole (OPC-14597)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $1080 | Check With Us |
| 50g | $1780 | Check With Us |
| 100g | $2670 | Check With Us |
: Cat #: V0991 CAS #: 129722-12-9 Purity ≥ 98%
Description: Aripiprazole (formerly OPC-14597; OPC 14597; OPC14597; trade name Abilify) is an approved atypical antipsychotic drug that acts as a high-affinity partial agonist of 5-HT receptor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 448.39 |
|---|---|
| Molecular Formula | C23H27Cl2N3O2 |
| CAS No. | 129722-12-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 90 mg/mL (200.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | OPC-14597; OPC 14597; OPC14597 |
| Protocol | In Vivo | Aripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties |
|---|---|---|
| Animal model | WAG/Rij rats (N = 6 per dose, 6 months, administration of a mixture of tiletamine/zolazepam) | |
| Dosages | 0, 0.3, 1, 3 mg/kg | |
| Administration | IP, 1 mL/kg, every day at 5 p.m. until the end of the experiments |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2302 mL | 11.1510 mL | 22.3020 mL | 44.6040 mL |
| 5mM | 0.4460 mL | 2.2302 mL | 4.4604 mL | 8.9208 mL |
| 10mM | 0.2230 mL | 1.1151 mL | 2.2302 mL | 4.4604 mL |
| 20mM | 0.1115 mL | 0.5576 mL | 1.1151 mL | 2.2302 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.