AMG 548 dihydrochloride
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2050 | To Be Confirmed |
| 200mg | $3075 | To Be Confirmed |
| 500mg | $5190 | To Be Confirmed |
: Cat #: V25155 CAS #: 864249-60-5 (free base) Purity ≥ 99%
Description: AMG-548 dihydrochloride is a novel, orally bioactive, potent and selective inhibitor of p38α with Ki of 0.5 nM.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 534.48 |
|---|---|
| Molecular Formula | C29H29Cl2N5O |
| CAS No. | 864249-60-5 (free base) |
| SMILES Code | O=C1N(C)C(NCC(N)CC2=CC=CC=C2)=NC(C3=CC=NC=C3)=C1C4=CC=C5C=CC=CC5=C4.Cl.Cl<br/> |
| Synonyms | AMG-548 dihydrochloride |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8710 mL | 9.3549 mL | 18.7098 mL | 37.4195 mL |
| 5mM | 0.3742 mL | 1.8710 mL | 3.7420 mL | 7.4839 mL |
| 10mM | 0.1871 mL | 0.9355 mL | 1.8710 mL | 3.7420 mL |
| 20mM | 0.0935 mL | 0.4677 mL | 0.9355 mL | 1.8710 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.