Alprenolol

This product is for research use only, not for human use. We do not sell to patients.

Alprenolol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$350To Be Confirmed
1g$550To Be Confirmed
5g$1485To Be Confirmed

Cat #: V33099 CAS #: 13655-52-2 Purity ≥ 99%

Description: Alprenolol (alfeprol, alpheprol) is a potent and non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.

References: Himori N, et al. Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs. Arch Int Pharmacodyn Ther. 1977 Jan;225(1):152-65.

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Molecular Weight (MW)249.35
Molecular FormulaC15H23NO2
CAS No.13655-52-2
ProtocolIn VivoAlprenolol (p.o., 50 mg/kg) causes a significant drop in blood pressure which averages 20 mm Hg (at 3-hr) and an increase in heart rate by 39 beats/min (at 3-hr) in conscious renal hypertensive dogs
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.0104 mL20.0521 mL40.1043 mL80.2085 mL
5mM0.8021 mL4.0104 mL8.0209 mL16.0417 mL
10mM0.4010 mL2.0052 mL4.0104 mL8.0209 mL
20mM0.2005 mL1.0026 mL2.0052 mL4.0104 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.