Aloe-emodin (Rhabarberone)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$350	Check With Us
5g	$1050	Check With Us
10g	$1575	Check With Us

: [email protected] [email protected]

Cat #: V2090 CAS #: 481-72-1 Purity ≥ 98%

Description: Aloe emodin (also known as NSC 38628, Rhabarberone; 3-Hydroxymethylchrysazine) is a hydroxyanthraquinone based and naturally occuring CFTR channel activator found in Aloe vera leaves, and has a specific in vitro and in vivo antitumor activity.

References: Huang PH, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition. Evid Based Complement Alternat Med. 2013;2013:376123.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	270.24
Molecular Formula	C15H10O5
CAS No.	481-72-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 3 mg/mL (11.1 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
SMILES Code	O=C(C1=C2C(O)=CC=C1)C3=CC(CO)=CC(O)=C3C2=O
Synonyms	NSC 38628; NSC38628; NSC-38628; Rhabarberone; 3-Hydroxymethylchrysazine; Aloe emodin;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.7004 mL	18.5021 mL	37.0041 mL	74.0083 mL
5mM	0.7401 mL	3.7004 mL	7.4008 mL	14.8017 mL
10mM	0.3700 mL	1.8502 mL	3.7004 mL	7.4008 mL
20mM	0.1850 mL	0.9251 mL	1.8502 mL	3.7004 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.