Albendazole (SKF-62979)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$199	Check With Us
10g	$345	Check With Us
20g	$1152	Check With Us

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Cat #: V1620 CAS #: 54965-21-8 Purity ≥ 98%

Description: Albendazole (formerly SKF-62979; SKF62979; SKF 62979; Zentel; Albenza; Eskazole; Valbazen), a benzimidazole analog and tubulin inhibitor, is an orally bioavailable anti-parasitic drug that has been approved for use in the treatment of various worm infestations such as giardiasis, neurocysticercosis, filariasis, hydatid disease, trichuriasis, pinworm disease, and ascariasis, among others.

References: Pourgholami MH, et al. In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. Cancer Lett. 2001 Apr 10;165(1):43-9.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	265.33
Molecular Formula	C12H15N3O2S
CAS No.	54965-21-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 17 mg/mL (64.1 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Synonyms	SKF-62979; Albendazole; SKF62979; Zentel; SKF 62979; Albenza; Eskazole; Valbazen

Protocol	In Vitro	Albendazole (100, 500, 1000 nM; 1, 3, or 5 days) inhibits cell proliferation in a dose-dependent manner
Protocol	In Vivo	Albendazole (300 mg/kg; p.o.; per day in two divided dose for 20 days) profoundly suppresses tumor growth in vivo

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.7689 mL	18.8445 mL	37.6889 mL	75.3778 mL
5mM	0.7538 mL	3.7689 mL	7.5378 mL	15.0756 mL
10mM	0.3769 mL	1.8844 mL	3.7689 mL	7.5378 mL
20mM	0.1884 mL	0.9422 mL	1.8844 mL	3.7689 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.