Triclabendazole (also known as CGA-89317; CGA89317; EGA-230B; Fasinex; NVP-EGA-230; Egaten) is a benzimidazole-based anthelmintic and fasciolicidal agent that acts as a tubulin inhibitor by binding to tubulin and impairing the intracellular transport mechanisms, thus interfering with protein synthesis.
CYT997 (also called Lexibulin; CYT-997; CYT 997) is a potent VDA-vascular disrupting agent and also a potent microtubule polymerization/mitotic inhibitor with potential anticancer activity.
Vinorelbine ditartrate (KW-2307; KW2307; Navelbine, Biovelbin, Eunades; Nor-5′-anhydrovinblastine), the ditartrate salt of vinorelbine which is an antimitotic agent, is a tubulin inhibitor and microtubule stablizer approved for cancer treatment.
Docetaxel Trihydrate (formerly RP-56976; NSC-628503; trade name Taxotere), the trihydrated form of docetaxel which is a paclitaxel analog, is a tubulin/mitotic inhibitor with a broad spectrum of antineoplastic activities.
Vinflunine tartrate (formerly BMS710485, F-12158, F12158, BMS-710485), the tartrate salt of Vinflunine, is a bi-fluorinated analog of the vinca alkaloid vinorelbine with potential antitumor activity.
Vinblastine (formerly NSC49842; NSC-49842; NSC 49842; Velban; Velsar; VLB; Vincaleukoblastine), a naturally occuring alkaloid isolated from the plant Vinca rosea Linn, is an approved anticancer drug acting as a potent mitotic inhibitor that inhibits microtubule assembly/formation.
Combretastatin A4 Phosphate Disodium (also called CA4P, Fosbretabulin; CA 4DP; CA-4P; Zybrestat) is the water-soluble prodrug that has to be activated to the active form, Combretastatin A4 (CA4), which is a highly potent MTA (microtubule-targeting agent) or tubulin inhibitor that acts as a potent anticancer agent that binds β-tubulin with a Kd of 0.4 μM […]
Combretastatin A4 (CA-4; CRC-87-09; Combretastatin A-4) is a highly potent tubulin/microtubule inhibitor or microtubule polymerization destablizer with potential antitumor activity.
Paclitaxel (also known as NSC-125973; BMS-181339-01; trade name taxol; Anzatax; Asotax; Bristaxol) is a highly potent microtubule polymer stabilizer (mitotic inhibitor that stabilizes the polymerization of tubulin) with an IC50 of 0.1 pM in human endothelial cells.=
INH6 (INH-6; INH 6) is a novel, potent and cell-permeable inhibitor of High expression in cancer 1 (Hec1) with potential anticancer activity.