Afloqualone

This product is for research use only, not for human use. We do not sell to patients.

Afloqualone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$550Check With Us
5g$950Check With Us
10g$1425Check With Us

Cat #: V28547 CAS #: 56287-74-2 Purity ≥ 99%

Description: Afloqualone (HQ-495; HQ495; HQ 495) is a centrally acting muscle relaxant and an agonist of GABA receptor with sedative and muscle-relaxant effects.

References: Y Kudo, et al. Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. Jpn J Pharmacol. 1989 Aug;50(4):515-9.

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Molecular Weight (MW)283.3064
Molecular FormulaC16H14FN3O
CAS No.56287-74-2
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5297 mL17.6487 mL35.2975 mL70.5949 mL
5mM0.7059 mL3.5297 mL7.0595 mL14.1190 mL
10mM0.3530 mL1.7649 mL3.5297 mL7.0595 mL
20mM0.1765 mL0.8824 mL1.7649 mL3.5297 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.