ADT-OH

This product is for research use only, not for human use. We do not sell to patients.

ADT-OH
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$550Check With Us
1g$900Check With Us
1μg$2275Check With Us

Cat #: V6483 CAS #: 18274-81-2 Purity ≥ 98%

Description: ADT-OH is a analogue of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor.

References: Cai F, et al. ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. Cell Death Dis. 2020;11(1):33.

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Product Promise

Promise
Molecular Weight (MW)226.34
Molecular FormulaC9H6OS3
CAS No.18274-81-2
SMILES CodeS=C1SSC(C2=CC=C(O)C=C2)=C1
SynonymsADT-OH; Desmethylanethol trithione; ACS1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4181 mL22.0907 mL44.1813 mL88.3626 mL
5mM0.8836 mL4.4181 mL8.8363 mL17.6725 mL
10mM0.4418 mL2.2091 mL4.4181 mL8.8363 mL
20mM0.2209 mL1.1045 mL2.2091 mL4.4181 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.