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Cat #: V3074 CAS #: 61955-05-3 Purity ≥ 98%
Description: A23887(A 23887 or A-23887) is a tetracyclic spiro amine which has previously been shown to have considerable affinity for dopamine D-2 receptors. It is important for defining the pharmacophore for D-2 antagonist activity due to its limited conformational freedom. This compound is important for defining the pharmacophore for D-2 antagonist activity due to their limited conformational freedom. Possible foldings of the multicyclic structure were energy minimized and the barriers for inversion and for rotation of the ammonium group were computed.
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Molecular Weight (MW) | 337.89 |
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Molecular Formula | C22H24ClN |
CAS No. | 61955-05-3 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: |
Water: | |
Ethanol: | |
Synonyms | A23887; A-23887; A 23887 |
Protocol | In Vitro | In vitro activity: Kinase Assay: Cell Assay: |
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Solvent volume to be added | Mass (the weight of a compound) | |||
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Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.9595 mL | 14.7977 mL | 29.5954 mL | 59.1909 mL |
5mM | 0.5919 mL | 2.9595 mL | 5.9191 mL | 11.8382 mL |
10mM | 0.2960 mL | 1.4798 mL | 2.9595 mL | 5.9191 mL |
20mM | 0.1480 mL | 0.7399 mL | 1.4798 mL | 2.9595 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.