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Cat #: V3089 CAS #: 335679-69-1 Purity ≥ 98%
Description: A-315675, a pyrrolidine-based compound, is a novel and potent anti-infuenza agent. It acts as a neuramidase inhibitor and responds well to resistant strains. A-315675 can inhibit A and B strain influenza virus neuraminidases in enzyme assays and influenza virus replication in cell culture. A-315675 effectively inhibited influenza A N1, N2, and N9 and B strain neuraminidases with inhibitor constant (K(i)) values between 0.024 and 0.31 nM. These values were comparable to or lower than the K(i) values measured for oseltamivir carboxylate (GS4071), zanamivir, and BCX-1812, except for the N1 enzymes that were found to be the most sensitive to BCX-1812.
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Molecular Weight (MW) | 326.44 |
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Molecular Formula | C17H30N2O4 |
CAS No. | 335679-69-1 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 10 mM |
Water: N/A | |
Ethanol: N/A | |
Synonyms | A315675; A-315675; A 315675 |
Solvent volume to be added | Mass (the weight of a compound) | |||
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Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.0634 mL | 15.3168 mL | 30.6335 mL | 61.2670 mL |
5mM | 0.6127 mL | 3.0634 mL | 6.1267 mL | 12.2534 mL |
10mM | 0.3063 mL | 1.5317 mL | 3.0634 mL | 6.1267 mL |
20mM | 0.1532 mL | 0.7658 mL | 1.5317 mL | 3.0634 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.