A 121 | CAS 68072-84-4

A 121

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Cat #: V3054 CAS #: 68072-84-4 Purity ≥ 98%

Description: Produced by an unidentified strain of Streptomyces species, A121 is a non-polyene antifungal antibiotic isolated and purified to homogeneity. As an antibiotic, A121 was found to be active against a number of filamentous fungi including some plant and human pathogens. On the basis of its infrared spectrum, proton magnetic resonance, mass spectra, and some chemical derivatives, a plausible chemical constitution of this antibiotic is proposed. Its antibiotic activity apparently requires the presence of an alpha-ketol system in the molecule.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	326.21
Molecular Formula	C18H30O5
CAS No.	68072-84-4
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Synonyms	A 121; A-121

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.0655 mL	15.3275 mL	30.6551 mL	61.3102 mL
5mM	0.6131 mL	3.0655 mL	6.1310 mL	12.2620 mL
10mM	0.3066 mL	1.5328 mL	3.0655 mL	6.1310 mL
20mM	0.1533 mL	0.7664 mL	1.5328 mL	3.0655 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.