A1-226 | CAS 59684-59-2

A1-226

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Cat #: V3055 CAS #: 59684-59-2 Purity ≥ 98%

Description: A1-226 is a cephalosporin antibiotic that belongs to the class of β-lactam antibiotics, it was originally isolated from the fungus called 'Acremonium', previously known as 'Cephalosporium'. It is a potassium salt that has the advantage of improved water solubility which is required for preparing a solution for IM injection.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	386.46
Molecular Formula	C16H15KN2O5S
CAS No.	59684-59-2
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Synonyms	A1-226, A1226

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5876 mL	12.9379 mL	25.8759 mL	51.7518 mL
5mM	0.5175 mL	2.5876 mL	5.1752 mL	10.3504 mL
10mM	0.2588 mL	1.2938 mL	2.5876 mL	5.1752 mL
20mM	0.1294 mL	0.6469 mL	1.2938 mL	2.5876 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.