A23887 | CAS 61955-05-3

A23887

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V3074 CAS #: 61955-05-3 Purity ≥ 98%

Description: A23887(A 23887 or A-23887) is a tetracyclic spiro amine which has previously been shown to have considerable affinity for dopamine D-2 receptors. It is important for defining the pharmacophore for D-2 antagonist activity due to its limited conformational freedom. This compound is important for defining the pharmacophore for D-2 antagonist activity due to their limited conformational freedom. Possible foldings of the multicyclic structure were energy minimized and the barriers for inversion and for rotation of the ammonium group were computed.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	337.89
Molecular Formula	C22H24ClN
CAS No.	61955-05-3
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO:
	Water:
	Ethanol:
Synonyms	A23887; A-23887; A 23887

Protocol	In Vitro	In vitro activity: Kinase Assay: Cell Assay:

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.9595 mL	14.7977 mL	29.5954 mL	59.1909 mL
5mM	0.5919 mL	2.9595 mL	5.9191 mL	11.8382 mL
10mM	0.2960 mL	1.4798 mL	2.9595 mL	5.9191 mL
20mM	0.1480 mL	0.7399 mL	1.4798 mL	2.9595 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.