Mestranol

This product is for research use only, not for human use. We do not sell to patients.

Mestranol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$235Check With Us
10g$1250Check With Us
20g$1875Check With Us

Cat #: V1739 CAS #: 72-33-3 Purity ≥ 98%

Description: Mestranol (Ethinyl Estradiol 3 Methyl Ether; Devocin; Norquen; Ovastol), the 3-methyl ether of ethinyl estradiol, is a potent estrogen receptor agonist that has been used as an oral contraceptive.

References: S Y Jiang, et al. Tamoxifen inhibits hepatoma cell growth through an estrogen receptor independent mechanism. J Hepatol. 1995 Dec;23(6):712-9.

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Molecular Weight (MW)310.43
Molecular FormulaC21H26O2
CAS No.72-33-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 15 mg/mL (48.3 mM)r
Water: <1 mg/mLr
Ethanol: 25 mg/mL (80.5 mM)
SynonymsEthinyl Estradiol 3 Methyl Ether; Devocin; Norquen; Ovastol; Ethynylestradiol 3-methyl ether; Ethinyl Estradiol 3-Methyl Ether
ProtocolIn VitroMestranol is a low potency synthetic estrogen that has been shown to be much more stable than 17β-Estradiol(HY-B0141) in hepatoma cell culture.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2213 mL16.1067 mL32.2134 mL64.4268 mL
5mM0.6443 mL3.2213 mL6.4427 mL12.8854 mL
10mM0.3221 mL1.6107 mL3.2213 mL6.4427 mL
20mM0.1611 mL0.8053 mL1.6107 mL3.2213 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.