VBIT-4 | CAS 2086257-77-2

VBIT-4

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1250	In Stock
250mg	$2000	In Stock
500mg	$3000	In Stock

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Cat #: V2258 CAS #: 2086257-77-2 Purity ≥ 98%

Description: VBIT-4 is a novel and potent inhibitor of VDAC1 (voltage-dependent anion channel 1), which is the outer mitochondrial membrane protein and a convergence point for a variety of cell survival and death signals, including apoptosis.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	457.88
Molecular Formula	C21H23ClF3N3O3
CAS No.	2086257-77-2

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1840 mL	10.9199 mL	21.8398 mL	43.6796 mL
5mM	0.4368 mL	2.1840 mL	4.3680 mL	8.7359 mL
10mM	0.2184 mL	1.0920 mL	2.1840 mL	4.3680 mL
20mM	0.1092 mL	0.5460 mL	1.0920 mL	2.1840 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.