Adenosine 5′-diphosphoribose sodium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $550 | To Be Confirmed |
| 250mg | $990 | To Be Confirmed |
| 500mg | $2475 | To Be Confirmed |
: Cat #: V39083 CAS #: 68414-18-6 Purity ≥ 99%
Description: Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a novel nicotinamide adenine nucleotide (NAD+) metabolite, and is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator.
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| Molecular Weight (MW) | 581.30 |
|---|---|
| Molecular Formula | C₁₅H₂₂N₅NaO₁₄P₂ |
| CAS No. | 68414-18-6 |
| Synonyms | Adenosine 5′diphosphoribose sodium |
| Protocol | In Vitro | In mouse embryonic fibroblasts (MEFs), H2O2 The treatment showed that activation of poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) produces Adenosine 5′-diphosphoribose sodium (ADP ribose), which is an activation signal of the TRPM2 channel that passes through extracellular Ca2+ Influx and/or lysosomes promote CA2+ Elevated Ca2+ Release. This process eventually activates early or late autophagy in response to varying degrees of oxidative stress |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7203 mL | 8.6014 mL | 17.2028 mL | 34.4056 mL |
| 5mM | 0.3441 mL | 1.7203 mL | 3.4406 mL | 6.8811 mL |
| 10mM | 0.1720 mL | 0.8601 mL | 1.7203 mL | 3.4406 mL |
| 20mM | 0.0860 mL | 0.4301 mL | 0.8601 mL | 1.7203 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.