AC1903 is a novel, potent and specific TRPC5 channel blocker with podocyte-protective activity, suppressing severe proteinuria and prevent podocyte loss.

Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a novel nicotinamide adenine nucleotide (NAD+) metabolite, and is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator.

SAR7334 is a novel, potent and orally bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo.

PF-4840154 is a novel, potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively.

TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes.

TRPM4-IN-5 is a novel and potent inhibitor of the cation channel TRPM4.

Dihydrocapsaicin is a naturally occuring capsaicin isolated from Capsicum fruit, it acts as a potent and selective TRPV1 agonist, and also increases p-Akt levels.

SKF-96365 HCl (SKF-96365 hydrochloride) is a novel, potent and selective TRPC channel blocker that is commonly used to characterize the potential functions of TRPC channels in different systems.

SB-366791 is a competitive and selective cinnamide TRPV1 (Vanilloid receptor 1) antagonist identified via high-throughput screening of a large chemical library.

Icilin (also known as AG-3-5 or AG 3-5) is a synthetic CMR1/TRPM8 (transient receptor potential M8) super-cooling agent/agonist that is 2.5-fold more efficacious and nearly 200-fold more potent than the reference cold thermosensory agonist, l-menthol.