CP-447697

This product is for research use only, not for human use. We do not sell to patients.

CP-447697
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$4500Check With Us
1g$7500Check With Us
5g$18950Check With Us

Cat #: V12980 CAS #: 1092847-21-6 Purity ≥ 99%

Description: CP447697 is a lipophilic C5a receptor antagonist which can be used for the research of inflammation.

References: Blagg J, et al. Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5601-4.

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Product Promise

Promise
Molecular Weight (MW)554.05
Molecular FormulaC29H26ClF2N3O2S
CAS No.1092847-21-6
SMILES CodeO=C(N1CCC(N(C(C2=CSC3=CC=CC=C23)=O)CCC4=CC=C(Cl)C=C4)CC1)NC5=CC=C(F)C=C5F
SynonymsCP-447697; CP 447697; CP447697;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8049 mL9.0245 mL18.0489 mL36.0978 mL
5mM0.3610 mL1.8049 mL3.6098 mL7.2196 mL
10mM0.1805 mL0.9024 mL1.8049 mL3.6098 mL
20mM0.0902 mL0.4512 mL0.9024 mL1.8049 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.