Catalog No: V40131
CAS No. (CAS Registry Number): 2055362-72-4
Description:

ADH-503 free base [(Z)-Leukadherin-1] is a novel, potent, selective, orally bioactive and allosteric agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.

Catalog No: V3627
CAS No. (CAS Registry Number): 1903742-34-6
Description:

Complement factor D-IN-2 (extracted from WO2015130838A1, compound 190) is an inhibitor of complement factor D with the potential to be used for treating autoimmune diseases.

Catalog No: V4614
CAS No. (CAS Registry Number): 1140525-25-2
Description:

SB290157 TFA, the trifluoroacetate salt of SB-290157, is a novel, potent and selective antagonist of complement anaphylatoxin C3a receptor (IC50 = 200 nM) with the potential to be used in arthritis, diet-induced obesity, and metabolic dysfunction.

Catalog No: V12980
CAS No. (CAS Registry Number): 1092847-21-6
Description:

CP447697 is a lipophilic C5a receptor antagonist which can be used for the research of inflammation.

Catalog No: V37572
CAS No. (CAS Registry Number): 2055362-74-6
Description:

ADH-503 [(Z)-Leukadherin-1 choline] is a novel, potent, selective, orally bioactive and allosteric agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.

Catalog No: V32062
CAS No. (CAS Registry Number): 1903768-17-1
Description:

Danicopan (ACH4471) is a novel, selective and orally bioavailable small-molecule factor D inhibitor, which inhibits alternative pathway of complement (APC) activity.

Catalog No: V31830
CAS No. (CAS Registry Number): 206645-99-0
Description:

Compstatin is a novel and potent 13-residue cyclic peptide acting as a potent inhibitor of the complement system C3 with species specificity.

Catalog No: V2514
CAS No. (CAS Registry Number): 1646321-63-2
Description:

Iptacopan (LNP-023; LNP023) HCl, the hydrochloride salt of Iptacopan, is an oral, potent and selective factor B inhibitor ( IC50 = 10 nM).

Catalog No: V33581
CAS No. (CAS Registry Number): 1210945-69-9
Description:

EG-00229 TFA, the trifluoroacetic acid form of EG00229, is a novel and potent Neuropilin 1 (NRP1) receptor antagonist with antitumor effects.