Complement factor D-IN-2
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1950 | Check With Us |
| 500mg | $3150 | Check With Us |
| 1g | $4725 | Check With Us |
: Cat #: V3627 CAS #: 1903742-34-6 Purity ≥ 99%
Description: Complement factor D-IN-2 (extracted from WO2015130838A1, compound 190) is an inhibitor of complement factor D with the potential to be used for treating autoimmune diseases.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 574.43 |
|---|---|
| Molecular Formula | C27H24BrN7O3 |
| CAS No. | 1903742-34-6 |
| SMILES Code | O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)[C@]5([H])C[C@]5([H])C1)NC6=NC(Br)=CC=C6 |
| Synonyms | Complement factor D-IN-2 |
| Protocol | In Vitro | Complement factor D-IN-2 reduces the excessive activation of complement factor D. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7409 mL | 8.7043 mL | 17.4086 mL | 34.8171 mL |
| 5mM | 0.3482 mL | 1.7409 mL | 3.4817 mL | 6.9634 mL |
| 10mM | 0.1741 mL | 0.8704 mL | 1.7409 mL | 3.4817 mL |
| 20mM | 0.0870 mL | 0.4352 mL | 0.8704 mL | 1.7409 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.