PA-6

This product is for research use only, not for human use. We do not sell to patients.

PA-6
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
250mg$1250Check With Us
500mg$1875Check With Us

Cat #: V18696 CAS #: 500715-03-7 Purity ≥ 98%

Description: PA-6 is a selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models.

References: Takanari H, et al. Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue. Cardiovasc Res. 2013 Jul 1;99(1):203-14.

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Product Promise

Promise
Molecular Weight (MW)492.623
Molecular FormulaC31H32N4O2
CAS No.500715-03-7
SynonymsPA-6
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0299 mL10.1497 mL20.2995 mL40.5990 mL
5mM0.4060 mL2.0299 mL4.0599 mL8.1198 mL
10mM0.2030 mL1.0150 mL2.0299 mL4.0599 mL
20mM0.1015 mL0.5075 mL1.0150 mL2.0299 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.