BMS-191095
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1900 | Check With Us |
| 250mg | $2950 | Check With Us |
| 500mg | $4425 | Check With Us |
: Cat #: V3481 CAS #: 166095-21-2 Purity ≥ 98%
Description: BMS-191095 is a novel and potent activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 408.88 |
|---|---|
| Molecular Formula | C₂₂H₂₁ClN₄O₂ |
| CAS No. | 166095-21-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent |
| Protocol | In Vivo | BMS-191095 (2.5 or 25 μg; Intraventricular perfusion, 30 min/60 min/24 hours before ischemia induction (1 time) reduces neuronal damage to rats by transient focal cerebral ischemia |
|---|---|---|
| Animal model | Male Wistar rats with the induction of ischemia induced by middle cerebral artery occlusion (MCAO) | |
| Dosages | 2.5 or 25 μg | |
| Administration | Intraventricular infusion; 30 min/60 min/24 hours before the induction of ischemia, once |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4457 mL | 12.2285 mL | 24.4571 mL | 48.9141 mL |
| 5mM | 0.4891 mL | 2.4457 mL | 4.8914 mL | 9.7828 mL |
| 10mM | 0.2446 mL | 1.2229 mL | 2.4457 mL | 4.8914 mL |
| 20mM | 0.1223 mL | 0.6114 mL | 1.2229 mL | 2.4457 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.