Diazoxide

This product is for research use only, not for human use. We do not sell to patients.

Diazoxide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$250Check With Us
2g$400Check With Us
5g$650Check With Us

Cat #: V4676 CAS #: 364-98-7 (free) Purity ≥ 98%

Description: Diazoxide (also known as Proglycem) is a potassium channel activator used to treat hyperinsulinism.

References: Coetzee WA, et al. Multiplicity of effectors of the cardioprotective agent, diazoxide. Pharmacol Ther. 2013 Nov;140(2):167-75.

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Product Promise

Promise
Molecular Weight (MW)230.67
Molecular FormulaC8H7ClN2O2S
CAS No.364-98-7 (free)
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VitroDiazoxide (Sch-6783) has a number of physiological effects, including lowering the blood pressure and rectifying hypoglycemia. Diazoxide has powerful protective properties against cardiac ischemia
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.3352 mL21.6760 mL43.3520 mL86.7039 mL
5mM0.8670 mL4.3352 mL8.6704 mL17.3408 mL
10mM0.4335 mL2.1676 mL4.3352 mL8.6704 mL
20mM0.2168 mL1.0838 mL2.1676 mL4.3352 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.