Esomeprazole sodium (S-Omeprazole sodium)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $280 | Check With Us |
| 1g | $390 | Check With Us |
| 5g | $1050 | Check With Us |
: Cat #: V1680 CAS #: 161796-78-7 Purity ≥ 98%
Description: Esomeprazole Sodium (formerly 18-sodium; H199; 18 sodium; H-199; Nexium IV; S-Omeprazole sodium), the sodium salt of esomeprazole, is the S-isomer of omeprazole which is a potent PPI-proton pump inhibitor with an IC50 of 0.076 mg/kg.
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- Related Biological Data
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| Molecular Weight (MW) | 367.4 |
|---|---|
| Molecular Formula | C17H18N3O3S.Na |
| CAS No. | 161796-78-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 73 mg/mL (198.7 mM)r |
| Water: 73 mg/mL (198.7 mM)r | |
| Ethanol: 73 mg/mL (198.7 mM) | |
| Synonyms | H-199; 18sodium; H 199; 18-sodium; H199; 18 sodium; Nexium IV |
| Protocol | In Vitro | Esomeprazole (25-100 µM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7218 mL | 13.6091 mL | 27.2183 mL | 54.4366 mL |
| 5mM | 0.5444 mL | 2.7218 mL | 5.4437 mL | 10.8873 mL |
| 10mM | 0.2722 mL | 1.3609 mL | 2.7218 mL | 5.4437 mL |
| 20mM | 0.1361 mL | 0.6805 mL | 1.3609 mL | 2.7218 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.