Tiaprofenic acid
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
2g | $480 | Check With Us |
5g | $880 | Check With Us |
10g | $1320 | Check With Us |
Cat #: V16407 CAS #: 33005-95-7 Purity ≥ 98%
Description: Tiaprofenic acid (Surgam, Surgamyl and Tiaprofen) is a non-steroidal anti-inflammatory drug (NSAID) approved for the treatment of pain, especially arthritic pain.
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Molecular Weight (MW) | 260.31 |
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Molecular Formula | C14H12O3S |
CAS No. | 33005-95-7 |
SMILES Code | CC(C1=CC=C(C(C2=CC=CC=C2)=O)S1)C(O)=O |
Synonyms | Tiaprofenic acid; trade names Surgam, Surgamyl and Tiaprofen. |
Protocol | In Vivo | Female Lewis rats received either Tiaprofenic acid (as an intravenous (iv.) bolus injection of 15 mg/kg and constant infusion of 0.02 mg/min) for 6 h. Tiaprofenic acid results in a significant decrease in serum sulfate concentrations and increase in sulfate clearance ratio. There is also a significant decrease in the fraction of sulfate reabsorbed by the kidneys. |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.8416 mL | 19.2079 mL | 38.4157 mL | 76.8315 mL |
5mM | 0.7683 mL | 3.8416 mL | 7.6831 mL | 15.3663 mL |
10mM | 0.3842 mL | 1.9208 mL | 3.8416 mL | 7.6831 mL |
20mM | 0.1921 mL | 0.9604 mL | 1.9208 mL | 3.8416 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.