Phenytoin (5,5-Diphenylhydantoin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $150 | Check With Us |
| 100g | $450 | Check With Us |
| 200g | $675 | Check With Us |
: Cat #: V1654 CAS #: 57-41-0 Purity ≥ 98%
Description: Phenytoin (also known as NCI-C55765; NCI C55765; NCIC55765; Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer that has been approved as an anticonvulsant for the treatment of seizures.
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| Molecular Weight (MW) | 252.27 |
|---|---|
| Molecular Formula | C₁₅H₁₂N₂O₂ |
| CAS No. | 57-41-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO : 100 mg/mL (396.40 mMr |
| Need ultrasonic)r | |
| H2O: N/Ar | |
| Ethanol: N/A | |
| Synonyms | NCI-C55765; NCI C55765; NCIC55765 |
| Protocol | In Vitro | Phenytoin is an antiepileptic drug. It is useful to partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9640 mL | 19.8200 mL | 39.6401 mL | 79.2801 mL |
| 5mM | 0.7928 mL | 3.9640 mL | 7.9280 mL | 15.8560 mL |
| 10mM | 0.3964 mL | 1.9820 mL | 3.9640 mL | 7.9280 mL |
| 20mM | 0.1982 mL | 0.9910 mL | 1.9820 mL | 3.9640 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.