Levobupivacaine HCl (S-Bupivacaine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $245 | Check With Us |
| 10g | $845 | Check With Us |
| 20g | $1265 | Check With Us |
: Cat #: V1651 CAS #: 27262-48-2 Purity ≥ 98%
Description: Levobupivacaine HCl [also known as (S)-(-)-Bupivacaine; Chirocaine, Novabupi], the hydrochloride salt of Levobupivacaine which is the pure S(-)-enantiomer of bupivacaine, is a reversible neuronal sodium channel inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 324.89 |
|---|---|
| Molecular Formula | C18H28N2O.HCl |
| CAS No. | 27262-48-2 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 64 mg/mL (197 mM)rr |
| Water: 64 mg/mL (197 mM)rr | |
| Ethanol: 57 mg/mL (175.4 mM) | |
| Synonyms | (S)-(-)-Bupivacaine HCl; Levobupivacaine, Levobupivacaine HCl; Levobupivacaine hydrochloride; Chirocaine, Novabupi |
| Protocol | In Vitro | Levobupivacaine (0-4 mM; 24 h) does not affect the viability of GES-1 cells but inhibits the viability of HGC27 and SGC7901 cells |
|---|---|---|
| In Vivo | Levobupivacaine (40 μmol/kg; IP; once daily for 25 days) significantly inhibits SGC7901 cell growth, and enhances the lipid ROS accumulation |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0780 mL | 15.3898 mL | 30.7796 mL | 61.5593 mL |
| 5mM | 0.6156 mL | 3.0780 mL | 6.1559 mL | 12.3119 mL |
| 10mM | 0.3078 mL | 1.5390 mL | 3.0780 mL | 6.1559 mL |
| 20mM | 0.1539 mL | 0.7695 mL | 1.5390 mL | 3.0780 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.