Nav1.7 inhibitor

This product is for research use only, not for human use. We do not sell to patients.

Nav1.7 inhibitor
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$750To Be Confirmed
50mg$1125To Be Confirmed
100mg$1685To Be Confirmed

Cat #: V33122 CAS #: 1355631-24-1 Purity ≥ 99%

Description: Nav1.7 inhibitor is a novel and potent Voltage-gated sodium channel inhibitor with potential usefulness in pain therapy and as a local anaesthetic.

References: Alan Daniel Brown, et al. Preparation of sulfonamide derivatives as Nav1.7 inhibitors. Patent WO2012007868A2.

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Promise
Molecular Weight (MW)426.67
Molecular FormulaC₁₅H₁₁Cl₃FNO₄S
CAS No.1355631-24-1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3437 mL11.7187 mL23.4373 mL46.8746 mL
5mM0.4687 mL2.3437 mL4.6875 mL9.3749 mL
10mM0.2344 mL1.1719 mL2.3437 mL4.6875 mL
20mM0.1172 mL0.5859 mL1.1719 mL2.3437 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.