DPI-201-106
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1450 | To Be Confirmed |
| 500mg | $2450 | To Be Confirmed |
| 1g | $3675 | To Be Confirmed |
: Cat #: V13770 CAS #: 97730-95-5 Purity ≥ 99%
Description: DPI-201-106 [(±)-SDZ-201 106] is a novel and potent inhibitor of the TTX-resistant h1 Na channel which is cardioselective.
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| Molecular Weight (MW) | 466.58 |
|---|---|
| Molecular Formula | C29H30N4O2 |
| CAS No. | 97730-95-5 |
| SMILES Code | N#CC(N1)=CC2=C1C=CC=C2OCC(O)CN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3 |
| Synonyms | DPI-201-106; (±)-SDZ-201 106; DPI201-106; DPI-201106; DPI 201106; DPI201106; SDZ201 106; SDZ-201106; SDZ 201 106; DPI 201-106; SDZ 201106; SDZ201106 |
| Protocol | In Vivo | In anesthetized dogs, left ventricular dP/dtmax is increased by DPI 201-106 0.2 mg/kg i.v.In digoxin-pretreated anesthetized cats, DPI 201-106 is infused up to an accumulated dose of 12.22 mg/kg i.v |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1433 mL | 10.7163 mL | 21.4326 mL | 42.8651 mL |
| 5mM | 0.4287 mL | 2.1433 mL | 4.2865 mL | 8.5730 mL |
| 10mM | 0.2143 mL | 1.0716 mL | 2.1433 mL | 4.2865 mL |
| 20mM | 0.1072 mL | 0.5358 mL | 1.0716 mL | 2.1433 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.