TLR4-IN-C34
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1250 | Check With Us |
| 1g | $1950 | Check With Us |
| 5g | $4935 | Check With Us |
: Cat #: V37647 CAS #: 40592-88-9 Purity ≥ 99%
Description: TLR4-IN-C34 is a novel and orally bioactive TLR4 inhibitor that reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis.
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| Molecular Weight (MW) | 389.40 |
|---|---|
| Molecular Formula | C17H27NO9 |
| CAS No. | 40592-88-9 |
| SMILES Code | CC(O[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1NC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)C |
| Synonyms | C34; C 34; C-34; TLR4-IN-C34; Toll-Like Receptor 4-C34; TLR4-C34; TLR4-C-34; TLR4-C 34; |
| Protocol | In Vitro | TLR4-IN-C34 (C34, 1 mg/kg, orally daily) could attenuate NEC severity and demonstrates a marked preservation of the intestinal mucosa. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5681 mL | 12.8403 mL | 25.6805 mL | 51.3611 mL |
| 5mM | 0.5136 mL | 2.5681 mL | 5.1361 mL | 10.2722 mL |
| 10mM | 0.2568 mL | 1.2840 mL | 2.5681 mL | 5.1361 mL |
| 20mM | 0.1284 mL | 0.6420 mL | 1.2840 mL | 2.5681 mL |
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The dilution calculator equation
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
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Number of animals
Step Two: Enter the in vivo formulation
%DMSO
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%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
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Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.