Loxoribine

This product is for research use only, not for human use. We do not sell to patients.

Loxoribine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$350To Be Confirmed
250mg$450To Be Confirmed
500mg$675To Be Confirmed

Cat #: V24425 CAS #: 121288-39-9 Purity ≥ 99%

Description: Loxoribine (7-Allyl-8-oxoguanosine; RWJ-21757) is a novel and potent immunostimulant agent acting as an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist.

References: Heil F, et al. The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol. 2003 Nov;33(11):2987-97.

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Molecular Weight (MW)339.30
Molecular FormulaC13H17N5O6
CAS No.121288-39-9
SMILES CodeOC[C@@H]1[C@H]([C@H]([C@H](N2C(N(CC=C)C3=C2N=C(N)NC3=O)=O)O1)O)O
SynonymsLoxoribine; Loxoribina; Loxoribinum; RWJ-21757; RWJ 21757; RWJ21757;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9472 mL14.7362 mL29.4724 mL58.9449 mL
5mM0.5894 mL2.9472 mL5.8945 mL11.7890 mL
10mM0.2947 mL1.4736 mL2.9472 mL5.8945 mL
20mM0.1474 mL0.7368 mL1.4736 mL2.9472 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.