Loxoribine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $350 | To Be Confirmed |
250mg | $450 | To Be Confirmed |
500mg | $675 | To Be Confirmed |
Cat #: V24425 CAS #: 121288-39-9 Purity ≥ 99%
Description: Loxoribine (7-Allyl-8-oxoguanosine; RWJ-21757) is a novel and potent immunostimulant agent acting as an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist.
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- Physicochemical and Storage Information
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Molecular Weight (MW) | 339.30 |
---|---|
Molecular Formula | C13H17N5O6 |
CAS No. | 121288-39-9 |
SMILES Code | OC[C@@H]1[C@H]([C@H]([C@H](N2C(N(CC=C)C3=C2N=C(N)NC3=O)=O)O1)O)O |
Synonyms | Loxoribine; Loxoribina; Loxoribinum; RWJ-21757; RWJ 21757; RWJ21757; |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.9472 mL | 14.7362 mL | 29.4724 mL | 58.9449 mL |
5mM | 0.5894 mL | 2.9472 mL | 5.8945 mL | 11.7890 mL |
10mM | 0.2947 mL | 1.4736 mL | 2.9472 mL | 5.8945 mL |
20mM | 0.1474 mL | 0.7368 mL | 1.4736 mL | 2.9472 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.