TLR7 agonist 2

This product is for research use only, not for human use. We do not sell to patients.

TLR7 agonist 2
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$3050Check With Us
200mg$4575Check With Us
500mg$7720Check With Us

Cat #: V4750 CAS #: 1642857-69-9 Purity ≥ 98%

Description: TLR7 agonist 2 is a novel, oral, potent and selective agonist of Toll-like Receptor 7 (TLR7) with antiviral activity.

References: McGowan DC, et al. Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B. J Med Chem. 2017 Jul 27;60(14):6137-6151.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)336.35
Molecular FormulaC₁₇H₁₆N₆O₂
CAS No.1642857-69-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeNC1=NC(OCC2=NOC(C)=C2)=C(N(CC3=NC=CC=C3)C=C4)C4=N1
SynonymsTLR7 Agonist 2, TLR7 Agonist2, TLR7 Agonist-2
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9731 mL14.8655 mL29.7309 mL59.4619 mL
5mM0.5946 mL2.9731 mL5.9462 mL11.8924 mL
10mM0.2973 mL1.4865 mL2.9731 mL5.9462 mL
20mM0.1487 mL0.7433 mL1.4865 mL2.9731 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.