Gabapentin

This product is for research use only, not for human use. We do not sell to patients.

Gabapentin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$150In Stock
10g$250In Stock
20g$375In Stock

Cat #: V1286 CAS #: 60142-96-3 Purity ≥ 98%

Description: Gabapentin HCl (Neurontin; Aclonium; Convalis; Gabapentin Stada), the hydrochloride salt of gabapentin which is a GABA analog, is an orally bioavailable medication that was approved for use in the treatment of seizures and neuropathic pain.

References: Fink K, et, al. Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130(4):900-6.

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Product Promise

Promise
Molecular Weight (MW)171.24
Molecular FormulaC9H17NO2
CAS No.60142-96-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 34 mg/mL (198.6 mM)r
Water:<1 mg/mLr
Ethanol: <1 mg/mL
SynonymsNeurontin; Gabapentin; Neurontin; Gabapentine; Gabapentin HCl; Gabapentin hydrochloride; Aclonium; Convalis; gabapentin; Gabapentin Hexal; Gabapentin Stada
ProtocolIn VitroGabapentin (0-300 μM) produces a concentration-dependent inhibition of the K+-induced [Ca2+]i increase in synaptosomes (IC50=14 μM; maximal inhibition by 36%)
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.8398 mL29.1988 mL58.3976 mL116.7951 mL
5mM1.1680 mL5.8398 mL11.6795 mL23.3590 mL
10mM0.5840 mL2.9199 mL5.8398 mL11.6795 mL
20mM0.2920 mL1.4599 mL2.9199 mL5.8398 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.