KY02111

This product is for research use only, not for human use. We do not sell to patients.

KY02111
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$950Check With Us
500mg$1440Check With Us
1g$2160Check With Us

Cat #: V1354 CAS #: 1118807-13-8 Purity ≥ 98%

Description: KY02111 (KY 02111; KY-02111) is a potent and selective inhibitor of the Wnt signaling pathway with important biological activity.

References: Minami I, et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep. 2012 Nov 29;2(5):1448-60.

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Product Promise

Promise
Molecular Weight (MW)376.86
Molecular FormulaC18H17ClN2O3S
CAS No.1118807-13-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 75 mg/mL (199.0 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsKY02111; KY 02111; KY-02111
ProtocolIn VitroKY02111 treatment with WNT signaling modulators produces robust cardiac differentiation of hPSCs in a xeno-free, defined medium, devoid of serum and any kind of recombinant cytokines and hormones, such as BMP4, Activin A, or insulin
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6535 mL13.2675 mL26.5351 mL53.0701 mL
5mM0.5307 mL2.6535 mL5.3070 mL10.6140 mL
10mM0.2654 mL1.3268 mL2.6535 mL5.3070 mL
20mM0.1327 mL0.6634 mL1.3268 mL2.6535 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.