Artesunate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $190 | Check With Us |
| 10g | $330 | Check With Us |
| 20g | $495 | Check With Us |
: Cat #: V2003 CAS #: 88495-63-0 Purity ≥ 98%
Description: Artesunate (Amivas; SM-804; WR-256283; HSDB-7458; Armax 200), an approved antimalaria agent, is a semisynthetic derivative of artemisinin with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 384.42 |
|---|---|
| Molecular Formula | C19H28O8 |
| CAS No. | 88495-63-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: > 10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(CCC(O)=O)=O)O[C@H]3[C@@]24[C@H]1CC[C@](OO4)(C)O3 |
| Synonyms | Amivas; SM-804; WR-256283; HSDB-7458; Armax 200; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458 |
| Protocol | In Vitro | Artesunate is an inhibitor of both STAT-3[1] and exported protein 1 (EXP1). |
|---|---|---|
| In Vivo | Tumor growth is significantly reduced in the group receiving combined treatment of Artesunate and cisplatin (P<0.01). In comparison, Artesunate alone has no significant effect on the growth of tumor xenografts for both cell lines. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6013 mL | 13.0066 mL | 26.0132 mL | 52.0264 mL |
| 5mM | 0.5203 mL | 2.6013 mL | 5.2026 mL | 10.4053 mL |
| 10mM | 0.2601 mL | 1.3007 mL | 2.6013 mL | 5.2026 mL |
| 20mM | 0.1301 mL | 0.6503 mL | 1.3007 mL | 2.6013 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.