RO8191

This product is for research use only, not for human use. We do not sell to patients.

RO8191
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$850To Be Confirmed
200mg$1275To Be Confirmed
500mg$2150To Be Confirmed

Cat #: V7042 CAS #: 691868-88-9 Purity ≥ 99%

Description: RO8191 (RO-8191; CDM-3008) is a novel and potent activator of JAK/STAT pathway and interferon α receptor type 2 (IFNAR2) with antiviral effects.

References: Hideyuki Konishi, et al. An Orally Available, Small-Molecule Interferon Inhibits Viral Replication. Sci Rep. 2012;2:259.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)373.21
Molecular FormulaC14H5F6N5O
CAS No.691868-88-9
SMILES CodeFC(C1=C2C=CC3=NC(C4=NN=CO4)=CN3C2=NC(C(F)(F)F)=C1)(F)
SynonymsRO8191; RO-8191; RO 8191; RO4948191; RO 4948191; RO-4948191;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6795 mL13.3973 mL26.7946 mL53.5891 mL
5mM0.5359 mL2.6795 mL5.3589 mL10.7178 mL
10mM0.2679 mL1.3397 mL2.6795 mL5.3589 mL
20mM0.1340 mL0.6699 mL1.3397 mL2.6795 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.