Carbamazepine (CBZ; NSC 169864)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $250 | Check With Us |
| 10g | $445 | Check With Us |
| 20g | $665 | Check With Us |
: Cat #: V1646 CAS #: 298-46-4 Purity ≥ 98%
Description: Carbamazepine (formerly also known as CBZ, NSC-169864, Carbatrol; Tegretol, Epitol), an approved anticonvulsant drug, is a potent sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.
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| Molecular Weight (MW) | 236.27 |
|---|---|
| Molecular Formula | C15H12N2O |
| CAS No. | 298-46-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 47 mg/mL (198.9 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 18 mg/mL (76.2 mM) | |
| Solubility In Vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80: 5 mg/mL |
| SMILES Code | O=C(C1=CC2=CC=CC=C2NC3=CC=CC=C13)N |
| Synonyms | Carbamazepine, Tegretol, Epitol |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.2324 mL | 21.1622 mL | 42.3245 mL | 84.6489 mL |
| 5mM | 0.8465 mL | 4.2324 mL | 8.4649 mL | 16.9298 mL |
| 10mM | 0.4232 mL | 2.1162 mL | 4.2324 mL | 8.4649 mL |
| 20mM | 0.2116 mL | 1.0581 mL | 2.1162 mL | 4.2324 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.