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Dioscin (CCRIS 4123)

This product is for research use only, not for human use. We do not sell to patients.

Dioscin (CCRIS 4123)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$650Check With Us
500mg$1050Check With Us
1g$1575Check With Us

Cat #: V1984 CAS #: 19057-60-4 Purity ≥ 99%

Description: Dioscin (CCRIS 4123; Collettiside III) is a naturally occuring saponin isolated from Polygonatum Zanlanscianense Pamp, showing antitumor activities.

References: Chen J, et al. Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family. J Huazhong Univ Sci Technolog Med Sci. 2014 Feb;34(1):125-30.

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Product Promise

Promise
Molecular Weight (MW)869.05
Molecular FormulaC45H72O16
CAS No.19057-60-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: > 10 mMr
Water: NAr
Ethanol: NA
SMILES CodeC[C@@H]1CC[C@]2(O[C@H]3C[C@H]4[C@@H]5CC=C6C[C@@H](O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O[C@@H]8O[C@H]([C@@H]([C@H]([C@H]8O)O)O)C)O)O[C@@H]9O[C@H]([C@@H]([C@H]([C@H]9O)O)O)C)CO)CC[C@@]6([C@H]5CC[C@@]4([C@H]3[C@@H]2C)C)C)OC1
SynonymsCCRIS 4123; Collettiside III
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.1507 mL5.7534 mL11.5068 mL23.0136 mL
5mM0.2301 mL1.1507 mL2.3014 mL4.6027 mL
10mM0.1151 mL0.5753 mL1.1507 mL2.3014 mL
20mM0.0575 mL0.2877 mL0.5753 mL1.1507 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.