Vinorelbine (KW-2307)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$530	Check With Us
500mg	$880	Check With Us
1g	$1320	Check With Us

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Cat #: V29535 CAS #: 71486-22-1 Purity ≥ 99%

Description: Vinorelbine (KW-2307; Nor-5'-anhydrovinblastine) is a potent antimitotic agent and a semisynthetic vinca alkaloid derived from the leaves of the periwinkle plant (Vinca rosea) used for the treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

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Molecular Weight (MW)	778.95
Molecular Formula	C45H54N4O8
CAS No.	71486-22-1
SMILES Code	[H][C@@]1([C@](C(OC)=O)(O)[C@H](OC(C)=O)[C@@]2(C=CCN3CC[C@@]41[C@@]32[H])CC)N(C)C5=C4C=C([C@@]6(C(OC)=O)C[C@]7([H])C=C(CC)C[N@@](C7)CC8=C6NC9=C8C=CC=C9)C(OC)=C5
Synonyms	Vinorelbine Free Base; HSDB7665; HSDB-7665; HSDB 7665

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.2838 mL	6.4189 mL	12.8378 mL	25.6756 mL
5mM	0.2568 mL	1.2838 mL	2.5676 mL	5.1351 mL
10mM	0.1284 mL	0.6419 mL	1.2838 mL	2.5676 mL
20mM	0.0642 mL	0.3209 mL	0.6419 mL	1.2838 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.