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Indole-3-carbinol (I3C)

This product is for research use only, not for human use. We do not sell to patients.

Indole-3-carbinol (I3C)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$200Check With Us
10g$350Check With Us
20g$525Check With Us

Cat #: V1995 CAS #: 700-06-1 Purity ≥ 98%

Description: Indole-3-carbinol (I3C; 3-Indolemethanol) is natural product produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables.

References: Wang S, et al. Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents. J Med Chem. 2015 Aug 27;58(16):6678-96.

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Product Promise

Promise
Molecular Weight (MW)147.18
Molecular FormulaC9H9NO
CAS No.700-06-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 29 mg/mL (197.0 mM)r
Water: 7 mg/mL (47.6 mM)r
Ethanol: 29 mg/mL (197.0 mM)
SMILES CodeO=C1N2[C@](C(NC3=C4C=CC=C3)=C4CC2)([H])N(C)C5=C1C=CC=C5
SynonymsI3C; 3-Indolemethanol.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.7944 mL33.9720 mL67.9440 mL135.8880 mL
5mM1.3589 mL6.7944 mL13.5888 mL27.1776 mL
10mM0.6794 mL3.3972 mL6.7944 mL13.5888 mL
20mM0.3397 mL1.6986 mL3.3972 mL6.7944 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.