Limonin | CAS 1180-71-8

Limonin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
1g	$290	Check With Us
2g	$520	Check With Us
10g	$875	Check With Us

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Cat #: V0734 CAS #: 1180-71-8 Purity ≥ 98%

Description: Limonin (also known as NSC-36508; Obaculactone; limonoate D-ring-lactone and limonoic acid di-delta-lactone), a naturally occurring limonoid, is a hexacyclic triterpenoid isolated in citrus fruits and other plants, which has antivirus and antitumor ability.

References: Han YL, Yu HL, Li D, et al. Inhibitory effects of limonin on six human cytochrome P450 enzymes and P-glycoprotein in vitro. Toxicol In Vitro. 2011 Dec;25(8):1828-33.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	470.51
Molecular Formula	C26H30O8
CAS No.	1180-71-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 44 mg/mL (93.5 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
SMILES Code	O=C1C[C@]2([H])OC(C)(C)[C@]3([H])CC([C@@]4(C)[C@@]56[C@@](O6)([H])C(O[C@@H](C7=COC=C7)[C@]5(C)CC[C@]4([H])[C@@]23CO1)=O)=O
Synonyms	Citro; Dictamnolactone; NSC36508; Limonin; Evodin; Limonine; NSC-36508; NSC 36508; Obaculactone.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1254 mL	10.6268 mL	21.2535 mL	42.5071 mL
5mM	0.4251 mL	2.1254 mL	4.2507 mL	8.5014 mL
10mM	0.2125 mL	1.0627 mL	2.1254 mL	4.2507 mL
20mM	0.1063 mL	0.5313 mL	1.0627 mL	2.1254 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.