Tenofovir disoproxil [Bis(POC)-PMPA; GS 4331)] is an antiretroviral drug and prodrug of Tenofovir, acting as a nucleotide reverse transcriptase inhibitor to prevent and treat HIV/AIDS and to treat chronic hepatitis B.

Fosamprenavir Calcium (Amprenavir phosphate; GW-433908) is a phosphate ester prodrug of Amprenavir with improved solubility.

Ritonavir (previously known as ABT-538; A-84538; RTV; ABT538, trade name: Norvir) is a L-valine derivative and potent inhibitor of HIV-1 protease used to treat HIV infection and AIDS.

Atazanavir Sulfate (also known as Latazanavir, Zrivada, Reyataz, BMS-232632), the sulfate salt form of atazanavir, is a HIV protease inhibitor (PI) for HIV/AIDs treatment with Ki of 2.66 nM in a cell-free assay.

Nelfinavir (also known as AG-1341), the mesylate salt of nelfinavir, is a novel, potent and orally bioavailable HIV-1 protease inhibitor antiviral effects.

Darunavir Ethanolate (DRV, TMC-114; UIC-94017; Trade name: Prezista), the ethanolate salt of darunavir, is a nonpeptidic HIV protease inhibitor/PI used in combination with other HIV medications to control HIV infection.

Pepstatin A (NSC-272671; NSC272671), a pentapeptide, is a potent and selective aspartic protease inhibitor which also inhibits HIV replication.

Darunavir (also known as TMC114; DRV, Trade name: Prezista among others) is a nonpeptidic HIV protease inhibitor and an antiretroviral medication used to treat and prevent HIV/AIDS.

Lopinavir (formerly known as ABT-378; trade names Kaletra; Aluvia), an FDA approved antiretroviral drug in 2000 for HIV treatment, is a highly potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.

Amprenavir (formerly VX-478; trade name Agenerase and Prozei), an FDA approved drug for treating HIV infections, is a potent PXR-selective agonist, and an HIV protease inhibitor with the IC50 of 0.6 nM on HIV-1 protease, it also weakly inhibits HIV-2 protease with IC50 value of 19 nM.