Nelfinavir mesylate (AG 1343)

This product is for research use only, not for human use. We do not sell to patients.

Nelfinavir mesylate (AG 1343)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$450To Be Confirmed
500mg$750To Be Confirmed
1g$1125To Be Confirmed

Cat #: V5184 CAS #: 159989-65-8 Purity ≥ 98%

Description: Nelfinavir (also known as AG-1341), the mesylate salt of nelfinavir, is a novel, potent and orally bioavailable HIV-1 protease inhibitor antiviral effects.

References: Mondal D, et al. Nelfinavir suppresses signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J. 2013 Spring;13(1):76-90.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)663.89
Molecular FormulaC33H49N3O7S2
CAS No.159989-65-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C([C@H]1N(C[C@@H](O)[C@@H](NC(C2=CC=CC(O)=C2C)=O)CSC3=CC=CC=C3)C[C@@]4([H])CCCC[C@@]4([H])C1)NC(C)(C)C.OS(=O)(C)=O.[H]O[H]
SynonymsViracept; Nelfinavir mesylate hydrate; AG-1343; AG 1343; AG1343; Nelfinavir;
ProtocolIn VitroNelfinavir (AG1341) Mesylate (1-10 μM; 48 hours) inhibits the proliferation of multiple myeloma cells.
In VivoNelfinavir Mesylate (75 mg/kg; i.p.; 5 days a week for 21 days) decreases multiple myeloma cell growth in NOD/SCID mice.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5063 mL7.5314 mL15.0627 mL30.1255 mL
5mM0.3013 mL1.5063 mL3.0125 mL6.0251 mL
10mM0.1506 mL0.7531 mL1.5063 mL3.0125 mL
20mM0.0753 mL0.3766 mL0.7531 mL1.5063 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.