Atazanavir Sulfate (Latazanavir, Zrivada, Reyataz, BMS232632)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$700	Check With Us
1g	$1150	Check With Us
5g	$2910	Check With Us

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Cat #: V0731 CAS #: 229975-97-7; Purity ≥ 98%

Description: Atazanavir Sulfate (also known as Latazanavir, Zrivada, Reyataz, BMS-232632), the sulfate salt form of atazanavir, is a HIV protease inhibitor (PI) for HIV/AIDs treatment with Ki of 2.66 nM in a cell-free assay.

References: Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	802.93
Molecular Formula	C38H52N6O7.H2SO4
CAS No.	229975-97-7;
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 104 mg/mL (129.5 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Solubility In Vivo	30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
SMILES Code	O=C(OC)N[C@@H](C(C)(C)C)C(NN(CC1=CC=C(C2=NC=CC=C2)C=C1)C[C@H](O)[C@H](CC3=CC=CC=C3)NC([C@H](C(C)(C)C)NC(OC)=O)=O)=O.O=S(O)(O)=O
Synonyms	BMS-232632; Atazanavir sulfate; BMS232632; BMS 232632

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.2454 mL	6.2272 mL	12.4544 mL	24.9088 mL
5mM	0.2491 mL	1.2454 mL	2.4909 mL	4.9818 mL
10mM	0.1245 mL	0.6227 mL	1.2454 mL	2.4909 mL
20mM	0.0623 mL	0.3114 mL	0.6227 mL	1.2454 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.