Remodelin

This product is for research use only, not for human use. We do not sell to patients.

Remodelin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$550Check With Us
500mg$745Check With Us
1g$1115Check With Us

Cat #: V2042 CAS #: 949912-58-7 Purity ≥ 98%

Description: Remodelin is a novel, selective and potent acetyl-transferase NAT10 inhibitor that is cell-permeable and stable analog of CPTH2.

References: Larrieu D, et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2;344(6183):527-32.

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Product Promise

Promise
Molecular Weight (MW)282.36
Molecular FormulaC15H14N4S
CAS No.949912-58-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 72 mg/mLr
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeN#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1
SynonymsRemodelin
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5416 mL17.7079 mL35.4158 mL70.8316 mL
5mM0.7083 mL3.5416 mL7.0832 mL14.1663 mL
10mM0.3542 mL1.7708 mL3.5416 mL7.0832 mL
20mM0.1771 mL0.8854 mL1.7708 mL3.5416 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.