Curcumin | CAS 458-37-7

Curcumin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
100g	$500	Check With Us
200g	$750	Check With Us
500g	$1265	Check With Us

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Cat #: V18876 CAS #: 458-37-7 Purity ≥ 99%

Description: Curcumin (Diferuloylmethane; NSC32982; Turmeric Yellow; curcumin I) is a naturally occurring diarylheptanoid diarylheptanoid with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities.

References: Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004

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Molecular Weight (MW)	368.38
Molecular Formula	C21H20O6
CAS No.	458-37-7
SMILES Code	O=C(CC(/C=C/C1=CC=C(O)C(OC)=C1)=O)/C=C/C2=CC=C(O)C(OC)=C2
Synonyms	Curcumin; Diferuloylmethane; Turmeric Yellow; curcumin I; C.I. 75300; Natural Yellow 3; NSC32982; UNIIIT942ZTH98

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.7146 mL	13.5729 mL	27.1459 mL	54.2918 mL
5mM	0.5429 mL	2.7146 mL	5.4292 mL	10.8584 mL
10mM	0.2715 mL	1.3573 mL	2.7146 mL	5.4292 mL
20mM	0.1357 mL	0.6786 mL	1.3573 mL	2.7146 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.