Remodelin HBr
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $569 | Check With Us |
500mg | $750 | Check With Us |
1g | $1125 | Check With Us |
Cat #: V2521 CAS #: 1622921-15-6 Purity ≥ 98%
Description: Remodelin HBr, the hydrobromide salt of Remodelin and a cell-permeable and stable analog of CPTH2, is an acetyl-transferase NAT10 inhibitor.
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Molecular Weight (MW) | 363.28 |
---|---|
Molecular Formula | C15H15BrN4S |
CAS No. | 1622921-15-6 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 72 mg/mL (198.2 mM)r |
Water: <1 mg/mLr | |
Ethanol: <1 mg/mL | |
SMILES Code | N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br |
Synonyms | Remodelin Hydrobromide; Remodelin HBr |
Protocol | In Vitro | Remodelin blocks invasion and migration of HCC cells in hypoxic conditions. |
---|---|---|
In Vivo | Remodelin (100 mg/kg; p.o) significantly reduces the loss of subcutaneous adipose tissue that is seen in the HGPS mouse model. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.7527 mL | 13.7635 mL | 27.5270 mL | 55.0540 mL |
5mM | 0.5505 mL | 2.7527 mL | 5.5054 mL | 11.0108 mL |
10mM | 0.2753 mL | 1.3763 mL | 2.7527 mL | 5.5054 mL |
20mM | 0.1376 mL | 0.6882 mL | 1.3763 mL | 2.7527 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.