RU.521 (RU320521)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1950 | Check With Us |
| 500mg | $2750 | Check With Us |
| 1g | $4125 | Check With Us |
: Cat #: V31403 CAS #: 2262452-06-0 Purity ≥ 98%
Description: RU.521 (RU320521) is a novel and selective cyclic GMP-AMP synthase (cGAS) inhibitor with potential usefulness for autoimmune diseases.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 415.23 |
|---|---|
| Molecular Formula | C19H12Cl2N4O3 |
| CAS No. | 2262452-06-0 |
| SMILES Code | O=C1OC(C2=C(O)N(C3=NC4=CC=C(Cl)C(Cl)=C4N3)N=C2C)C5=C1C=CC=C5 |
| Synonyms | RU320521; RU-320521; RU 320521; RU521; RU-521; RU 521; RU.521; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4083 mL | 12.0415 mL | 24.0830 mL | 48.1661 mL |
| 5mM | 0.4817 mL | 2.4083 mL | 4.8166 mL | 9.6332 mL |
| 10mM | 0.2408 mL | 1.2042 mL | 2.4083 mL | 4.8166 mL |
| 20mM | 0.1204 mL | 0.6021 mL | 1.2042 mL | 2.4083 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.