Etomoxir Sodium salt
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | In Stock |
| 500mg | $1650 | In Stock |
| 1g | $2475 | In Stock |
: Cat #: V2625 CAS #: 828934-41-4 Purity ≥ 98%
Description: Etomoxir sodium salt, the sodium salt form of etomoxir, is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane.
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| Molecular Weight (MW) | 320.74 |
|---|---|
| Molecular Formula | C15H18ClO4.Na |
| CAS No. | 828934-41-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 64 mg/mL (199.5 mM)r |
| Water: 64 mg/mL (199.5 mM)r | |
| Ethanol: 13 mg/mL (40.5 mM) | |
| SMILES Code | O=C([C@]1(CCCCCCOC2=CC=C(Cl)C=C2)OC1)[O-].[Na+] |
| Synonyms | Etomoxir sodium; B 807-54; B807-54; B-807-54; B 80754; B80754; B-80754; |
| Protocol | In Vitro | Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. |
|---|---|---|
| In Vivo | Etomoxir significantly inhibits the decrease of bone mineral density (BMD) and bone breaking strength in db/db and high fat (HF)-fed mice and suppresses the reduction of BMSCs-differentiated osteoblasts. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1178 mL | 15.5890 mL | 31.1779 mL | 62.3558 mL |
| 5mM | 0.6236 mL | 3.1178 mL | 6.2356 mL | 12.4712 mL |
| 10mM | 0.3118 mL | 1.5589 mL | 3.1178 mL | 6.2356 mL |
| 20mM | 0.1559 mL | 0.7794 mL | 1.5589 mL | 3.1178 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.